Process for producing phosphinylamino acid derivatives.

摘要

A process for producing a phosphinylamino acid derivative of the formula: <CHEM> wherein R<1> is a lower alkyl group, R<2> is a hydrogen atom, a lower alkyl group, a halo-lower alkyl group or a substituted or unsubstituted phenyl group, and R<3> is a substituted or unsubstituted alkyl group or a substituted or unsubstituted phenyl group, which comprises reacting a compound of the formula: <CHEM> wherin R<1> and R<2> are as defined above, and/or a compound of the formula: <CHEM> wherein R<1> and R<2> are as defined above, with a compound of the formula: R<3>CONH2 (IV) wherein R<3> is as defined above, carbon monoxide and hydrogen in the presence of a catalyst containing a metal of Group VIII of the Periodic Table.