发明名称 Phospholipase A2 inhibitors
摘要 There is disclosed a method for the treatment of immunoinflammatory conditions, such as allergy, anaphylaxis, asthma and inflammation in mammals which comprises administering to a mammal so afflicted an effective amount of a compound having the formula: <IMAGE> wherein R1 and R2 are each, independently, hydrogen, hydroxy, lower alkyl, lower alkoxy, haloloweralkyl, haloloweralkyl sulfony., halo or nitro; R3 is hydrogen, lower alkyl, or aryl of 7-12 carbon atoms; X is <IMAGE> A is -CH2-,-O- or -S-; m is 0-8; n is 0-7, with the proviso that m+n</=8; or a pharmacologically acceptable salt thereof; and also novel compounds of the above formula in which X is <IMAGE>
申请公布号 US4788304(A) 申请公布日期 1988.11.29
申请号 US19870129259 申请日期 1987.12.07
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 MARSHALL, LISA A.;STEINER, KURT E.;SCHIEHSER, GUY A.
分类号 C07D303/48;(IPC1-7):C07D303/48 主分类号 C07D303/48
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