发明名称 |
Nucleoside trichlorodimethylethyl phosphite esters |
摘要 |
Novel trichlorodimethylethyl phosphite esters are utilized as intermediates in a new synthesis procedure for producing oligonucleotides. On completion of the synthesis the trichlorodimethylethyl protecting group can be cleaved by reaction with tributylphosphine or hexamethylphosphoramide.
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申请公布号 |
US4786724(A) |
申请公布日期 |
1988.11.22 |
申请号 |
US19850758681 |
申请日期 |
1985.07.25 |
申请人 |
NORTHWESTERN UNIVERSITY |
发明人 |
LETSINGER, ROBERT L. |
分类号 |
C07H21/00;(IPC1-7):C07H19/10;C07H19/20;C07H19/207 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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