| 摘要 |
PURPOSE:To provide the titled agent containing glutathione monoalkyl ester or its salt as an active component. CONSTITUTION:An agent for reducing side-effect of cisplatin can be produced by using a compound of formula (R is alkyl) [e.g. glutathione monoisopropyl ester (isopropyl gamma-L-glutamyl-L-cysteinylglycinate) sulfate] or its salt as an active component. The agent is formed in the form of tablet, powder, grain, granule, capsule, solution, injection, etc., and is administered by oral or parenteral administration at a daily rate of 100-1,000mg per person for oral administration or 10-100mg per person for parenteral administration simultaneous to or in several doses before and after the administration of cisplatin.
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