摘要 |
A cephem compound of the formula:
<CHEM>
wherein
R<1> is amino substituted thiazolyl which may have halogen(s),
protected amino substituted thiazolyl which may have halogen(s),
lower alkylamino substituted thiazolyl, amino substituted thiadiazolyl,
protected amino-substituted thiadiazolyl, amino substituted pyridyl,
protected amino substituted pyridyl, furyl, thiazolyl, thiadiazolyl, phenyl, or naphthyl,
R<2> is carboxy(lower)alkyl or protected carboxy(lower)alkyl,
R<3> is lower alkylthio, and
R<4> is carboxy or protected carboxy,
and pharmaceutically acceptable salts thereof, and processes for their preparation, and also a pharmaceutical composition comprising, as an active ingredient, the above compound or its pharmaceutically acceptable salt.
<??>The invention also relates to intermediate compounds. |