VACCINE COMPOSITION FOR ANIMALS INFECTIOUS TO CANINE DISTEMPER VIRUS, INACTIVATION OF SAID VIRUS AND PREVENTION THEREBY

摘要

A vaccine composition for animals susceptible to infection by canine distemper virus. The vaccine comprises a small but immunologically effective amount of an inactivated canine distemper virus in combination with a non-toxic pharmaceutically acceptable immunologic adjuvant. A preferred method of inactivation of canine distemper virus by either exposure of the virus to an inactivating effective amount of binary ethyleneimine or alternatively exposure of the virus to long wavelength ultraviolet light in the presence of a furocoumarin.