发明名称 |
Drug delivery device, its preparation and use |
摘要 |
A device suitable for the topical administration of a pharmacologically active agent to an animal is described. The device comprises an active agent impermeable barrier layer, a reservoir containing the active agent which is in contact with the inner surface of the barrier layer and a removable protector layer in contact with the other surface of the reservoir. The reservoir comprises a fibrous mat into which the pharmacologically active agent is incorporated either by dissolving in the polymer forming the mat or by impregnation of a preformed mat. Alternative forms of the reservoir comprise a fibre mat coated on a skin contacting surface with a pressure sensitive adhesive and a fibre mat contained within a gel matrix. The device may be used to deliver nitroglycerin, oxybutynin or phenazocine transdermally.
|
申请公布号 |
US4784857(A) |
申请公布日期 |
1988.11.15 |
申请号 |
US19870057904 |
申请日期 |
1987.06.02 |
申请人 |
SMITH AND NEPHEW ASSOCIATED COMPANIES PLC |
发明人 |
BERRY, PETER W.;HOLDEN, PAUL |
分类号 |
A61M37/00;A61K9/70;A61L15/00;A61L15/44;(IPC1-7):A61F13/00 |
主分类号 |
A61M37/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|