发明名称 |
REAGENT HAVING WAVESTRENGTH PECULIAR CELL TOXICITY |
摘要 |
A group of hydro-monobenzoporphyrins "green porphyrins" (Gp) having absorption maxima in the range of 670-720 nanometers is useful in treating disorders which are subject to hematoporphyrin derivative (HPD) treatment in the presence of light. The use of the Gp of the invention permits the irradiation to comprise wavelengths other than those absorbed by blood. The Gp of the invention may also be conjugated to receptor ligands or to specific immunoglobulins or fragments thereof to target specific tissues or cells for the radiation treatment. Use of these materials permits lower levels of drug to be used, thus preventing side reactions which might destroy normal tissues.
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申请公布号 |
JPS63277700(A) |
申请公布日期 |
1988.11.15 |
申请号 |
JP19880011837 |
申请日期 |
1988.01.20 |
申请人 |
UNIV BRITISH KORONBIA:THE |
发明人 |
JIYURIA JII REBII;DEIBITSUDO DORUFUIN;JIYATSUKU KEI CHIYOU |
分类号 |
G01N33/53;A61K31/40;A61K38/22;A61K39/395;A61K41/00;A61P35/00;C07D487/22;C07K14/00;C07K14/575;C07K14/61;C07K16/00 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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