发明名称 PRODUCTION OF ASCORBIC ACID-2-PHOSPHATE
摘要 PURPOSE:To efficiently produce the titled compound from ascorbic acid or araboascorbic acid and ATP, by cultivating a specific bacterium or by using a cell of bacterium, a supernatant liquid or a treated material of the cell as an enzyme source. CONSTITUTION:A bacterium belonging to the genus Aeromonas, Klebsiella, Flavobacterium, Pseudomonas, Bacillus or Beneckea, capable of producing AsA2P (ascorbic acid-2-phosphate) from ascorbic acid or araboascorbic acid and ATP, is cultivated in a medium containing a carbon source, a nitrogen source and an inorganic substance at 25-35 deg.C at pH6.5-7.5 for 10-100hr. Ascorbic acid or araboascorbic acid and ATP are brought into contact with the medium during cultivation, a culture solution of the bacterium, a cell, a supernatant liquid of the culture solution or a treated material thereof, preferably a surface active agent and an organic solvent are optionally added to the reaction solution and the reaction is carried out to produce AsA2P.
申请公布号 JPS63273489(A) 申请公布日期 1988.11.10
申请号 JP19870319746 申请日期 1987.12.17
申请人 KYOWA HAKKO KOGYO CO LTD 发明人 FUJIO TATSURO;MARUYAMA AKIHIKO
分类号 C12P17/04;C12R1/01;C12R1/125;C12R1/20;C12R1/22;C12R1/38 主分类号 C12P17/04
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