发明名称 Amino acyl cephalosporin derivatives
摘要 Antibacterial cephalosporin compounds of the Formula (I): <IMAGE> (I) wherein W is a pharmaceutically acceptable salt or a carboxyl-protecting group; n is an integer from 1 to 2; -X- is -X1- where the X1 moieties are the same or different and selected from the group consisting of (D) or (L) <IMAGE> Y is -O-; wherein R1 is selected from the group consisting of: <IMAGE> R2 is H, -CH2R4, -CHR52 or -CR53, wherein R4 is H, F, Cl, Br, -OH, -CN, <IMAGE> -CH(CH3)2, -CH2(OH), <IMAGE> or -C 3BOND CH, where Q1, Q2 and Q3 are the same or different and selected from the group consisting of H, F, Cl or Br; R5 is F, Cl or Br; and Z1 is H or an amino protecting group.
申请公布号 US4783443(A) 申请公布日期 1988.11.08
申请号 US19860835280 申请日期 1986.03.03
申请人 THE UNIVERSITY OF CHICAGO 发明人 JOHNSTON, MICHAEL A.;MOBASHERY, SHAHRAIR
分类号 A61K31/545;C07D501/26;C07D501/28;C07D501/30;C07D501/34;C07D501/36;C07D501/46;(IPC1-7):C07D501/46 主分类号 A61K31/545
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