摘要 |
NEW MATERIAL:The isoflavan derivative of formula (R1 is methyl; R2 is methyl or H). USE:Useful as a muscle relaxant. It has microcirculation improving action and exhibits hypotensive action against essential hypertension, coronary vasodilating action, cerebral circulation improving action, action to ameliorate peripheral blood flow disorder (Raynaud's disease, Buerger disease etc.), etc. PREPARATION:KANZO (Glycyrrhiza glauba) is immersed in an organic solvent, the extract is treated by liquid chromatography an the compound of formula is separated from the eluate. The organic solvent is methanol, ethanol, acetone, etc., or their mixture. KANZO is a leguminous plant and its root and stolon have been long used as herb drugs.
|