| 发明名称 |
13-AZA-14-OXO-TXA2 ANALOGUES |
| 摘要 |
A novel 13-aza-14-oxo-TXA2 analogue of general formula: <IMAGE> (III) wherein symbol A represents -CH2CH2-(CH2)m-, cis-CH=CH-(CH2)m-, -CH2O-(CH2)m-, -S-(CH2)m- <IMAGE> R2 represents a bond or a straight or branched alkylene or alkenylene group of from 1 to 10 carbon atom(s) unsubstituted or substituted; R3 represents (i) a phenyl, phenoxy or phenylthio group unsubstituted or substituted, (ii) a straight or branched alkyl, alkenyl or alkynyl group of from 1 to 6 carbon atom(s) unsubstituted or substituted, (iii) a cycloalkyl, cycloalkyloxy or cycloalkylthio group of from 4 to 7 carbon atoms unsubstituted or substituted, (iv) a naphthyl, indolyl or indanyl group, or (v) an amino group unsubstituted or substituted R4 represents a hydrogen atom or a methyl group. |
| 申请公布号 |
DE3565255(D1) |
申请公布日期 |
1988.11.03 |
| 申请号 |
DE19853565255 |
申请日期 |
1985.06.12 |
| 申请人 |
ONO PHARMACEUTICAL CO., LTD. |
发明人 |
MIYAKE, HAJIMU;OKEGAWA, TADAO;KAWASAKI, AKIYOSHI |
| 分类号 |
A61K31/215;A61K31/19;A61K31/195;A61K31/22;A61P11/00;A61P43/00;C07C33/14;C07C51/367;C07C59/11;C07C67/00;C07C231/00;C07C233/52;C07C233/63;C07C233/81;C07C235/14;C07C235/26;C07C235/28;C07C235/30;C07C235/34;C07C235/40;C07C237/04;C07C237/14;C07C237/16;C07C237/18;C07C237/20;C07C313/00;C07C323/52;C07C405/00;C07D209/18;(IPC1-7):C07C103/38;C07C103/42;C07C103/30;C07C103/46;C07C149/32;C07C149/26;C07C125/065;C07C127/15;C07C177/00;C07C103/00;A61K31/00 |
主分类号 |
A61K31/215 |
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