| 摘要 |
<p>An array of molecular chains (24, 26) is added to a dielectric material between two electrodes (12, 14) of a capacitive affinity sensor (10). Such an array of molecular chains (24, 26) greatly changes dielectric properties between the two electrodes (12, 14) to greatly enhance sensitivity of the sensor (10). In a sensor (10) using direct binding, a viral fragment (36) is bound to the sensor's surface (34). A molecular chain, comprising an anti-viral antibody (38), an anti-human antibody (40), and a protein molecule (42), binds to the viral fragment (36). In a sensor (10) using competitive binding a hapten (52) is bound to the sensor's surface (34). A molecular chain, comprising an antibody (54) with attached aliphatic hydrocarbons (56), binds to the hapten (52). A free analyte (60) competes with the hapten (52) to bind with the antibody (54).</p> |
