Calcium-phosphate type hydroxyapatite for chromatographic separation and process for producing same

摘要

A calcium-phosphate type hydroxyapatite for chromatographic separation is in the form of spherulites having a mean particle diameter of 0.5 to 50 mu m, preferably 1 to 10 mu m. The spherulites are each an aggregate mainly of acicular crystallites belonging to a series of hexagonal systems and having unit lattice constants of 9.58+/-0.08 ANGSTROM for the a axis and 7.00+/-0.05 ANGSTROM for the c axis. The hydroxyapatite is produced by granulating a calcium-phosphate type hydroxyapatite in the form of a gel and then firing the granular apatite at 400 DEG to 700 DEG C., preferably at 500 DEG to 600 DEG C. The firing is performed by heating the granules in the presence of oxygen or air for a given period of time.