发明名称 CARCINOSTATIC AGENT
摘要 PURPOSE:To provide a carcinostatic agent containing a compound selected from cinnamaldehyde, alpha-methyl-cinnamaldehyde, beta-furfuracrolein, 2-methoxy-5- acetyl-benzaldehyde, etc., as an active component. CONSTITUTION:The objective carcinostatic agent for oral or parenteral adminis tration contains a compound selected from cinnamaldehyde, alpha-methyl- cinnamaldehyde, beta-furfuracrolein, 2-methoxy-5-acetyl-benzaldehyde, 4-ethoxyi sophthalaldehyde and 4-chloro-6-methylisophthalaldehyde. The carcinostatic agent is characterized by higher activity against initial cancer cancerized by SV40 oncogenic virus than activity against transplanted cancer and has low toxicity. The amount of the active component in the carcinostatic agent is 0.3-15.0wt.% for oral administration or transmucosal absorption and 0.01-10wt.% for parenteral administration.
申请公布号 JPS63264409(A) 申请公布日期 1988.11.01
申请号 JP19880005483 申请日期 1988.01.13
申请人 RIKAGAKU KENKYUSHO;KOCHI MUTSUYUKI;KAKEN PHARMACEUT CO LTD 发明人 TAKEUCHI SETSUO;KOCHI MUTSUYUKI;KAWARADA AKIRA;ESUMI SHINICHIRO;SASAKI KAZUYA;KAWABATA SHOZO;SAIDA TSUNEO;INOUE YUKIO;YAMAMOTO TADASU;SEKINE TAKAHARU;AMAMIYA KOJI;SAGA KATSUMASA
分类号 C07D307/46;A61K31/11;A61K31/34;A61K31/341;A61P35/00;C07C47/232;C07C47/457;C07C47/47 主分类号 C07D307/46
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