发明名称 NOVEL MILBEMYCINS AND PRODUCTION THEREOF
摘要 NEW MATERIAL:A compound expressed by formula I [V represents H, Oh or oxo; W represents H, OH, halogen atom or 4'-(alpha-L-oleandrosyl)-alpha-L- oleandrosyloxy; X represents methyl, ethyl, isoprophyl, sec-butyl, 1-methyl-1- propenyl, 1-methyl-1-butenyl, etc., when V represents H, and represents 1- methyl-1-propenyl, etc., when V represents OH or oxo; Y represents OH or hydroxyiminop Z represents H or OH]. EXAMPLE:30-Hydroxymilbemycin A4. USE:An insecticidal, miticidal and antiparasitic agent and an intermediate for producing other compounds. PREPARATION:A microorganism, belonging to genus Amycolata, Amycolatopsis, Streptomyces, Absidia, Circinella, Mucor, Syncephalastrum, Mortierella, Rhizopus or Bacillus and capable of converting a compound expressed by formula II or a substrate into a compound expressed by formula I is cultured in a medium.
申请公布号 JPS63264484(A) 申请公布日期 1988.11.01
申请号 JP19870304011 申请日期 1987.12.01
申请人 SANKYO CO LTD 发明人 NAKAGAWA KEIKO;TORIGATA AKIO;SATO KAZUO;KAJINO HISAYOSHI
分类号 C12P17/18;A01N43/90;A61K31/365;A61P33/00;A61P33/10;C07D307/00;C07D309/00;C07D313/00;C07D493/22;C07H17/08;C12R1/01;C12R1/11;C12R1/465;C12R1/645;C12R1/785;C12R1/845 主分类号 C12P17/18
代理机构 代理人
主权项
地址