发明名称 CARCINOSTATIC AGENT
摘要 PURPOSE:To obtain a carcinostatic agent exhibiting high sensitivity to a cell cancerized by SV40 oncogenic virus, by using a specific aromatic aldehyde derivative as an active component. CONSTITUTION:The objective carcinostatic agent contains sodium salt of a benzaldehyde-sulfurous acid addition compound, monobenzalpentaerythritol, N-benzylideneethylamine, N-benzylidenemethylamine, N-benzylideneisobutylamine, 1-benzylideneamino-2-ethoxyethane, 1-benzylideneamino-3-dimethylaminopropane, 1-benzylideneamino-2-propanol, 2-benzylideneamino-2-methylpropanol, 3- benzylideneamino-1-propene, 2-benzaldoxime, 3-ethyl-2-phenyloxazolidine, 3-(2'- hydroxyethyl)-2-phenyloxazoline and/or mandelonitrile as active components. The agent has low toxicity and exhibits characteristic carcinostatic action different from the mechanism of conventional chemotherapeutic agent for cancer.
申请公布号 JPS63264411(A) 申请公布日期 1988.11.01
申请号 JP19880005484 申请日期 1988.01.13
申请人 RIKAGAKU KENKYUSHO;KOCHI MUTSUYUKI;KAKEN PHARMACEUT CO LTD 发明人 TAKEUCHI SETSUO;KOCHI MUTSUYUKI;KAWARADA AKIRA;ESUMI SHINICHIRO;SASAKI KAZUYA;KAWABATA SHOZO;SAIDA TSUNEO;INOUE YUKIO;YAMAMOTO TADASU;SEKINE TAKAHARU
分类号 A61K31/185;A61K31/11;A61K31/15;A61K31/275;A61K31/335;A61K31/42;A61K31/421;A61K31/425;A61P35/00;C07D263/04 主分类号 A61K31/185
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