发明名称 |
PRODUCTION OF IMMUNOGENS BY ANTIGEN CONJUGATION TO LIPOSOMES |
摘要 |
<p>The invention disclosed relates to antigen/liposome conjugates, wherein the antigen is covalently bound to lipid molecules in the surface membrane of liposome vesicles, and wherein at least about 25 g of antigen is provided per mole of lipid. Enhanced immunogenicity is achieved by injecting the antigen/liposome conjugate so formed into an appropriate vertebrate host to produce antibodies.</p> |
申请公布号 |
CA1243946(A) |
申请公布日期 |
1988.11.01 |
申请号 |
CA19840459707 |
申请日期 |
1984.07.25 |
申请人 |
MAJESTY (HER) IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER O |
发明人 |
SHEK, PANG;HEATH, TIMOTHY D.;PAPAHADJOPOULOS, DEMETRIOS |
分类号 |
A61K9/127;A61K39/385;A61K39/39;(IPC1-7):A61K39/385 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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