摘要 |
5-Phenyl-5H-indeno[1,2-d]pyrimidine and ???? thereof are useful for inhibiting aromatase for treating or preventing estrogen dependent doses. The compounds have the formula <CHEM> wherein Y is hydrogen, methyl, hydroxy, methoxy, ????, fluoro, or -NHCOCH3; R1 is hydrogen, chloro, fluoro, methoxy, or flouromethyl; and each of R2 and R3 is independently hydrogen, ????, fluoro, or trifluoromethyl. |