发明名称 1-Phenyl-3-naphthalenyloxy-propanamines.
摘要 <p>The present invention provides 1-phenyl-3-naphthalenyloxypropanamines of formula (I) &lt;CHEM&gt; wherein: each of R&lt;1&gt; and R&lt;2&gt; independently is hydrogen or methyl; R&lt;3&gt; is hydrogen, halo, C1-C4, alkyl, C1-C3 alkoxy or trifluoromethyl; each R&lt;4&gt; independently is hydrogen, halo, C1-C4 alkyl, C1-C3 alkoxy or trifluoromethyl; m is 1 or 2; when m is 2, each R&lt;4&gt; can be combined to form methylenedioxy; or a pharmaceutically acceptable acid addition salt thereof. These compounds are selective inhibitions of serotonin uptake.</p>
申请公布号 EP0288188(A1) 申请公布日期 1988.10.26
申请号 EP19880303177 申请日期 1988.04.08
申请人 ELI LILLY AND COMPANY 发明人 ROBERTSON, DAVID WAYNE;THOMPSON, DENNIS CHARLES;WONG, DAVID TAIWAI
分类号 A61K31/135;A61K31/357;A61K31/36;A61P1/14;A61P3/04;A61P25/04;A61P25/20;A61P25/28;A61P25/30;A61P43/00;C07C67/00;C07C213/00;C07C213/02;C07C213/06;C07C217/48;C07C217/54;C07C217/64;C07D317/58;(IPC1-7):C07C93/00;C07C93/14 主分类号 A61K31/135
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