发明名称 DERIVATIVES OF INDANE,THE PROCESS FOR THEIR PREPARATION,THE NEW INTERMEDIATES OBTAINED,THEIR USE AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 The invention relates to new compounds of formula I and their salts: <IMAGE> in which: R1 and R2 are H or (1 to 5 C)alkyl or form a (3 to 6 C)cycloalkyl radical containing an O, S or N; A and B represent: - either <IMAGE> R = H or (1 to 5 C)alkyl, Z is a linear -(CH2)n- (n = 0 to 5) or branched (2 to 8 C)alkylene chain, X and X' are H, (1 to 4 C)alkyl, (1 to 4 C)alkoxy, halogen, OH, CF3, NO2, NH2 or NHalc1, - or <IMAGE> R3 and R4 are H or (1 to 5 C)alkyl or form, with the nitrogen to which they are bonded, a 5- or 6-membered heterocycle containing O, N or S; A and B cannot both be chosen from one of these 2 amino groups. Another subject of the invention is a process for the preparation of the compounds I, the new intermediates obtained, the application as medicaments of the compounds I and the compositions containing them.
申请公布号 ZA8706143(B) 申请公布日期 1988.10.26
申请号 ZA19870006143 申请日期 1987.08.19
申请人 ROUSSEL-UCLAF 发明人 FRANCOIS CLEMENCE;ODILE LE MARTRET;FRANCOISE DELEVALLEE;MICHEL FORTIN
分类号 C07D295/135;C07D311/96 主分类号 C07D295/135
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