发明名称 Methods for treating gout with chalcone derivatives.
摘要 <p>Certain chalcone derivatives are reported to inhibit the polymerization of tubulin to form microtubules and are therefore antimitotic agents which can be used to control the growth of tumor tissue and can be used as antigout agents. The chalcone derivatives are also reported to inhibit the destruction of the myelin sheath in the central nervous system of multiple schlerosis patients and are thus useful in controlling the progressive nature of the disease.</p>
申请公布号 EP0287901(A1) 申请公布日期 1988.10.26
申请号 EP19880105541 申请日期 1988.04.07
申请人 MERRELL DOW PHARMACEUTICALS INC. 发明人 EDWARDS, MICHAEL L.;STEMERICK, DAVID M.;SUNKARA, SAI P.
分类号 A61K31/165;(IPC1-7):C07C97/10;A61K31/135;C07C103/42 主分类号 A61K31/165
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