Esters of N-alkyl-nortropines and their quaternary derivatives having anti-bronchospastic activity, and pharmaceutical compositions containing them

摘要

The esters of N-alkyl-nortropines with phenyl-cyclohexen-carboxylic and phenyl-cyclohexen-acetic acids and their quaternary ammonium derivatives with alkyl halides and alkyl sulphates having general formula: <IMAGE> <IMAGE> and <IMAGE> whereas R'=-, -H, -CH3, -CH2-CH3, -CH2-CH2-CH3, -CH(CH3)2, -CH2-CH2-CH2-CH3, -CH2CH-(CH3)2 X-=Cl, Br, I, CH3SO4 show anti-bronchospastic activity. The invention relates also to the processes for their preparation and to the pharmaceutical compositions containing them.