发明名称 ANTITUMOR-ACTIVE SUBSTANCE AND PRODUCTION THEREOF
摘要 PURPOSE:To readily and inexpensively obtain the titled substance with high antitumor activity and low toxicity without microbial pollution, by heat-treating plant seeds, adding an aqueous solvent and an enzymatic agent, and extracting and purifying a protein component. CONSTITUTION:Plant seeds (processed product) are initially heat-treated and then an aqueous solvent and an enzymatic agent are added thereto. From the solution, are extracted a protein component and a proteinic substance is purified from the extract to afford the aimed substance. More specifically, a raw material is thermally sterilized at 60-120 deg.C, and an aqueous solvent, such as acetic acid, and an enzymatic agent, such as protease, are added thereto and extraction is carried out at 3-50 deg.C for 2-20 days. The extract is filtered and ammonium sulfate is added to the resultant filtrate to form precipitates, which are recovered and purified to afford the aimed substance.
申请公布号 JPS63258498(A) 申请公布日期 1988.10.25
申请号 JP19870092683 申请日期 1987.04.15
申请人 TAMANOISU KK 发明人 OSHIO TATSUICHIRO;KUBOTA AKIMASA;OKI YUJI;HARAMAKI YUKARI;SAITO FUMIO
分类号 C12P21/00;A61K36/00;A61K38/00;A61P35/00;C07K14/37;C07K14/41;C07K14/415 主分类号 C12P21/00
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