发明名称 ORGANISM COMPATIBILITY PROMOTER
摘要 PURPOSE:To obtain an organism compatibility promoter containing a compound obtained by treating a protein toxin such as toxin of Vibrio cholerae with an amino group chemically modified substance in a specific ratio as an active ingredient. CONSTITUTION:An organism compatibility promoter containing a compound [e.g. a compound shown by the formula (R1 is toxin of Vibrio cholerae; R2 is chemically modified group obtained by replacing hydrogen atom of primary amino group of protein R1; n is 1-10 with the proviso that n is 1-8 when R1 is viscotoxin)] obtained by treating 1mol. protein toxin selected from toxin of Vibrio cholerae, abrin (obtained from seed of Abrus precatorius L), ricin (protein belonging to albumin having ethanol poison factor and blood aggregation factor) and viscotoxin (peptide toxin contained in Viscum albam L to become a heart toxin) with 1-10mol. chemically modifying substance (e.g. polyethylene oxide) as an active ingredient.
申请公布号 JPS63253028(A) 申请公布日期 1988.10.20
申请号 JP19870086632 申请日期 1987.04.08
申请人 KAO CORP 发明人 OKAZAKI KIYOTAKA;HARA KENJI
分类号 A61K35/74;A61K38/00;A61P37/06 主分类号 A61K35/74
代理机构 代理人
主权项
地址