发明名称 |
Use of a prostaglandin in combination with an adrenergic blocking agent for reduction of intraocular pressure. |
摘要 |
<p>This invention provides a method for treating ocular hypertension or glaucoma in a subject's eye. The method comprises contacting the surface of the eye with an effective intraocular pressure reducing amount of a mixture of an adrenergic blocking agent and a prostaglandin or prostaglandin derivative in an ophthalmically compatible carrier, so as to reduce the intraocular pressure of the eye and maintain such reduced intraocular pressure. This invention also provides a composition for topical treatment of ocular hypertension or glaucoma in the eye of a subject. The composition comprises an effective intraocular pressure reducing amount of a mixture of an adrenergic blocking agent and a prostaglandin or prostaglandin derivative in an ophthalmically compatible carrier.</p> |
申请公布号 |
EP0286903(A1) |
申请公布日期 |
1988.10.19 |
申请号 |
EP19880104999 |
申请日期 |
1988.03.28 |
申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;PHARMACIA AB |
发明人 |
BITO, LASZLO Z;STJERNSCHANTZ, JOHAN WILHELM |
分类号 |
A61K31/41;A61K31/135;A61K31/535;A61K31/557;A61P27/02;A61P27/06 |
主分类号 |
A61K31/41 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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