Method of monitoring the progressive destruction of articular cartilage in a joint

摘要

PCT No. PCT/SE84/00257 Sec. 371 Date May 2, 1985 Sec. 102(e) Date May 2, 1985 PCT Filed Jul. 10, 1984 PCT Pub. No. WO85/01353 PCT Pub. Date Mar. 28, 1985.Method of determining changes occurring in articular cartilage. The method involves (a) quantifying proteoglycan monomer and/or antigenic fragments thereof in a synovial fluid sample and (b) correlating the values thus obtained with progressive destructions in the articular cartilage appertaining to that sample fluid.