发明名称 Dihydroquinolinone derivatives, processes for their preparation, medicaments containing them and their use, and intermediate products for their preparation
摘要 Compounds of the formula I <IMAGE> (I) where R(1), R(2), R(3), R(4) and R(5) are, inter alia, hydrogen and alkyl, m is 1-4, n is 0 or 1, p is 0-4 and R(6) is identical or different dialkylamine derivatives, and salts thereof, have a calcium-antagonistic action. They are obtained by reacting corresponding amines with a compound II which carries, on the side chain, a leaving group which can be displaced nucleophilically, or from a hydroxyphenyl-dihydroquinolin-2-one compound by reaction with a corresponding side chain compound which has a leaving group which can be displaced nucleophilically.
申请公布号 US4778793(A) 申请公布日期 1988.10.18
申请号 US19860886740 申请日期 1986.07.18
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 HENNING, RAINER;LERCH, ULRICH;KAISER, JOACHIM
分类号 A61K31/47;A61K31/495;A61K31/535;A61P3/00;A61P3/14;A61P9/00;C07D215/22;C07D215/227;C07D401/12;C07D491/056;(IPC1-7):A61K31/495 主分类号 A61K31/47
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