| 摘要 |
The invention relates to new compounds of the general Formula I <IMAGE> (I) and isomers thereof wherein R1 is C1-10 alkyl, C3-6 cycloalkyl or phenyl, naphthyl or phenyl-(C1-4 alkyl), wherein the aryl ring of the three latter groups may optionally bear one or more halogen, nitro, trifluoromethyl, amino, hydroxy, C1-4 alkyl and/or C1-4 alkoxy substituent(s); R2 stands for hydrogen, halogen, hydroxy, oxo, C1-4 alkyl, C1-4 alkoxy, phenyl or naphthyl, wherein the two latter groups may optionally bear one or more halogen, nitro, trifluoromethyl, amino, hydroxy, C1-4 alkyl and/or C1-4 alkoxy substituent(s); R3 represents hydrogen, hydroxy or C1-4 alkoxy; Z is buta-1,3-dienyl or a group of the general Formula (a) <IMAGE> (a) or (b) <IMAGE> (b) and X is hydrogen or halogen. The compounds of the general Formula I possess useful pharmacological properties, particularly antidepressant and antiarrhythmial effect. |
