发明名称 |
ANTITUMOR AGENT AND PROCESS FOR MANUFACTURING SAID AGENT |
摘要 |
This invention relates to an antitumor agent comprising as a main ingredient a chemically purified cell walls of microorganisms belonging to genus Bificobacterium having physical integrity of cell wall structure thereof, obtained without being subjected to chemical and/or physical destruction of said cell wall during removal of intracellular substances of said cell, and a process for manufacturing the same, which comprises the steps of; (a) treating said cells with surfactants, (b) treating said cells with proteases, nucleases, organic solvents and dilute acid, to remove intracellular substances out of said cells without destruction thereof, and (c) separating a chemically purified cell walls having physical integrity of cell wall structure thereof. |
申请公布号 |
DE3377920(D1) |
申请公布日期 |
1988.10.13 |
申请号 |
DE19833377920 |
申请日期 |
1983.12.23 |
申请人 |
MORINAGA MILK INDUSTRY CO., LTD. |
发明人 |
HASHIMOTO, YOSHIYUKI;TOIDA, TOMOHIRO;SEKINE, KAZUNORI;SAITO, MINORU;KAWASHIMA, TAKUJI;KUBOYAMA, MORIO |
分类号 |
A61K35/74;A61P35/00;C12P1/04;(IPC1-7):C12P1/04 |
主分类号 |
A61K35/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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