发明名称 |
NOVEL GLYCERIN DERIVATIVE, PRODUCTION THEREOF AND DRUG COMPOSITION CONTAINING SAID DERIVATIVE |
摘要 |
NEW MATERIAL:A compound shown by formula I [R<1> is 10-22C alkyl; R<2> is 1-6C acyl or benzoyl; Q is methylene and at least one methylene existing in -(Q)l contains at least one of alkyl or aryl as substituent group; l is 1-4; Y is nitrogen-containing heterocyclic ring containing group shown by formula II (R<3> and R<4> are H or 1-6C alkyl) as ring-forming group or nitrogen-containing hetero crosslinking ring group containing group shown by formula III or formula IV as ring-forming group; R<5>-R<7> are H, 1-6C alkyl, aryl or aralkyl]. EXAMPLE:2-Acetyloxy-3-hexadecyloxypropyl erythro-1,1-dimethylpyrrolidinio-2- ylphenylmethyl phosphate. USE:An inhibitor of blood platelet aggregation. PREPARATION:A compound shown by formula V is acylated with an acylating agent containing 1-6C acyl group or benzoyl group shown by R2.
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申请公布号 |
JPS63246387(A) |
申请公布日期 |
1988.10.13 |
申请号 |
JP19870080706 |
申请日期 |
1987.03.31 |
申请人 |
NIPPON CHEMIPHAR CO LTD |
发明人 |
MAZAKI MITSUO;TAKEDA HIROMITSU;KAMISHIRO TOSHIRO;YAMAMOTO MASAO |
分类号 |
A61K31/685;A61P7/02;A61P9/12;A61P11/00;A61P29/00;A61P35/00;A61P37/08;C07F9/10;C07F9/572;C07F9/59 |
主分类号 |
A61K31/685 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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