发明名称 |
METHOD OF MANUFACTURING TUBES FROM COLLAGEN, AND ITS USE IN THE FIELD OF VASCULAR PROSTHESES AND NERVOUS SYSTEMS |
摘要 |
A process for preparing collagen tubes includes extruding an aqueous gel containing about 1.5% native collagen through a cylindrical spinneret equipped with a central concentric tube designed to receive a part of a coagulation bath, followed by coagulation of the internal and external walls of the tube, leaving the spinneret in a coagulation bath constituted by about 70% acetone and 30% ammonia, followed by drying. Following drying, the collagen tube may be subjected to reticulation by dehydration carried out at about 80 DEG C. under a pressure of about 0.1 mm of Hg (vacuum) for about 24 hours. The reticulated collagen tube may eventually be subjected to a treatment which permits the introduction of azide groups onto the molecule without requiring that the collagen be coupled to any external molecule. |
申请公布号 |
EP0156740(B1) |
申请公布日期 |
1988.10.12 |
申请号 |
EP19850420025 |
申请日期 |
1985.02.19 |
申请人 |
BIOETICA, SOCIETE ANONYME |
发明人 |
HUC, ALAIN;GIMENO, RENE |
分类号 |
A61L27/00;A61F2/00;A61F2/06;A61L17/00;A61L27/24;B29C47/00;(IPC1-7):A61F2/06 |
主分类号 |
A61L27/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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