摘要 |
PURPOSE:To easily obtain the titled compound useful as an antidote, fatigue- relieving agent, tonic and nutrient agent, etc., in high purity and yield at a low cost, by adding ethylenimine to an aqueous solution of sulfurous acid and adjusting the pH of the solution with a base. CONSTITUTION:An aqueous solution of sulfurous acid is added with less than equimolar amount of ethylenimine based on sulfurous acid. The mixture is further added with at least one kind of inorganic bases selected from ammonia, alkali metal hydroxide, alkali metal carbonate and alkali metal sulfite to adjust the pH of the reaction liquid to >=4 and to start the reaction. The temperature of the system is maintained to <=40 deg.C during the addition of the inorganic base and the reaction is carried out at 10-60 deg.C for 2-10hr to obtain the objective compound.
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