POLY(DEOXYRIBONUCLEOTIDES), PHARMACEUTICAL COMPOSITIONS, USE AND PREPARATION OF THE POLY(DEOXYRIBONUCLEOTIDES)

摘要

The invention relates to poly(deoxyribonucleotides) containing methylated phosphate bridges between the deoxyribonucleoside units. Such novel compounds may be used for therapy, diagnosis and hybridisation purposes if the base sequence is specific for particular target DNA, such as bacterial, viral, parasitic or tumor cell DNA. The novel compounds form more stable duplex structures than natural DNA molecules.