发明名称 |
Method of inhibiting interleukin-1 release. |
摘要 |
<p>Methods useful for inhibiting the release of interleukin-1 and for alleviating interleukin-1 mediated conditions, such as IL-1-mediated inflammation, comprising administration of an effective amount of a pharmaceutically acceptable antioxidant compound such as disulfiram, tetrakis [3-(2,6-di-tert-butyl-4-hydroxyphenyl)propionyloxy methyl]methane or 2,4-di-isobutyl-6-(N,N-dimethylaminomethyl)-phenol.</p> |
申请公布号 |
EP0284879(A2) |
申请公布日期 |
1988.10.05 |
申请号 |
EP19880104085 |
申请日期 |
1988.03.15 |
申请人 |
MERRELL DOW PHARMACEUTICALS INC. |
发明人 |
KU, GEORGE;DOHERTY, NIALL |
分类号 |
A61K31/325;A61K31/135;A61K31/145;A61K31/215;A61K31/27;A61P3/08;A61P3/10;A61P9/10;A61P17/00;A61P29/00;A61P43/00;C07C69/73 |
主分类号 |
A61K31/325 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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