发明名称 Method of inhibiting interleukin-1 release.
摘要 <p>Methods useful for inhibiting the release of interleukin-1 and for alleviating interleukin-1 mediated conditions, such as IL-1-mediated inflammation, comprising administration of an effective amount of a pharmaceutically acceptable antioxidant compound such as disulfiram, tetrakis [3-(2,6-di-tert-butyl-4-hydroxyphenyl)propionyloxy methyl]methane or 2,4-di-isobutyl-6-(N,N-dimethylaminomethyl)-phenol.</p>
申请公布号 EP0284879(A2) 申请公布日期 1988.10.05
申请号 EP19880104085 申请日期 1988.03.15
申请人 MERRELL DOW PHARMACEUTICALS INC. 发明人 KU, GEORGE;DOHERTY, NIALL
分类号 A61K31/325;A61K31/135;A61K31/145;A61K31/215;A61K31/27;A61P3/08;A61P3/10;A61P9/10;A61P17/00;A61P29/00;A61P43/00;C07C69/73 主分类号 A61K31/325
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