发明名称 |
Diazonium compounds useful as components for nucleic acid probes |
摘要 |
This invention relates to a diazonium compound of the formula: <IMAGE> wherein Z is selected from the group consisting of biotin, an antigen, an antibody, a photoreactive group, a fluorescent group and heavy metal-containing compounds; X is an alkylene group containing up to 18 carbon atoms in the principle chain and a total of up to 24 carbon atoms or a substituted alkylene group containing up to 18 carbon atoms in the principle chain with substituents selected from the group consisting of solubility-enhancing groups and cleavable -S-S- containing moieties; Ar is an unsubstituted or substituted aryl or heteroaryl; and Y is an anion and n is an integer from 1-3. Such compounds are useful as components for nucleic acid probes.
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申请公布号 |
US4775745(A) |
申请公布日期 |
1988.10.04 |
申请号 |
US19860939370 |
申请日期 |
1986.12.08 |
申请人 |
NATIONAL DISTILLERS AND CHEMICAL CORPORATION |
发明人 |
FORD, JOHN P.;ERLANGER, BERNARD F.;BLEWETT, C. WILLIAM |
分类号 |
C12Q1/68;(IPC1-7):C07C113/00;C07C113/04 |
主分类号 |
C12Q1/68 |
代理机构 |
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地址 |
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