| 摘要 |
PURPOSE:To make good use of resources while converting a marine product oil such as fish oil which was low in utility value hitherto to lactones having wide uses, by oxidizing highly unsaturated fatty acids, introducing a hydroxyl group in the fatty acids, subjecting the fatty acids to intra-ring closure in order to provide the lactones. CONSTITUTION:A purified product or crude purified product of highly unsaturated fatty acid containing much in a marine product oil or fat such as fish oil, especially linoleic acid, arachidonic acid, eicosapentaenoic acid, docosahexaenoic acid or lower alcohol ester thereof is oxidized to introduce hydroxy group or dihydroxy group, which is then subjected to oxidation cleavage to provide hydroxy group and terminal carboxylic acid which are further ring-closed to synthesize the lactones. Thus the aimed stable lactones having wide uses as polyester raw material, perfume, organic intermediate, etc., and having various ring size are obtained in good yield from a marine product oil such as fish oil existing in relatively large quantities and readily available, but limited in uses.
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