发明名称 PROCEDE DE PREPARATION DE COMPOSE B-LACTAMIQUE ET INTERMEDIAIRES POUR SA SYNTHESE .
摘要 <p>There are disclosed a beta -lactam compound represented by the formula (I): <CHEM> wherein R1 and R2 are independently a hydrogen atom or a lower alkyl group; M is a hydrogen atom, a protective group or an eliminatable group which is easily hydrolyzable in a human body; R' and R'' are independently a hydrogen atom or a protective group; A is a mercapto group substituted by a substituted or unsubstituted polycyclic nitrogen-containing heterocyclic ring or a group represented by the following formula (a): -OOCNR3R4 (a) where R3 and R4 are independently a hydrogen atom or a lower alkyl group, provided that R1 and R2 are both hydrogen atoms, both R3 and R4 being hydrogen atoms are excluded, or its pharmaceutically acceptable salt, and a method for preparing the same, medicinal composition for microbism therapy containing the same and intermediates for synthesis of the same.</p>
申请公布号 MA21148(A1) 申请公布日期 1988.10.01
申请号 MA19870021280 申请日期 1987.07.20
申请人 NIPPON PHARMACEUTICAL DEVELOPMENT INSTITUTE COMPANY LIMITED;SANKEI PHARMACEUTICAL COMPANY LTD 发明人
分类号 C07B;C07D;C07D277/38;C07D501/34;C07D519/00;(IPC1-7):A61K/A 主分类号 C07B
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