ANALOGIFOERFARANDE FOER FRAMSTAELLNING AV TERAPEUTISKT ANVAENDBART 4-(1-IMIDATZOLYLMETYL)KANELSYRAHYDROKLORID- MONOHYDRAT.

摘要

4-(1-Imidazolylmethyl)cinnamic acid hydrochloride monohydrate of the formula: and pharmaceutical compositions containing such compound. The imidazole derivative above has a strong and specific inhibitory effect on thromboxane synthetase from human or bovine platelet microsomes, and is useful as a therapeutical agent for inflammation, hypertension, thrombus, cerebral apoplexy, and asthma.