发明名称 MANUFACTURE OF DISPERSION COLLOID SYSTEM OF MICROCAPSULE TYPE SUBSTANCE
摘要 The process according to the invention comprises: (1) the preparation of a liquid phase consisting essentially of a solution of a substance A in a solvent or in a mixture of solvents, and containing the substance B in solution or as a dispersion, (2) the preparation of a second liquid phase consisting essentially of a non-solvent or a mixture of non-solvents for the substances A and B, and supplemented with one or more surfactants, the solvent or mixture of solvents of the first phase being miscible in all proportions with the non-solvent or mixture of non-solvents of the second phase, (3) the addition of the first phase to the second phase with moderate agitation so as to produce a colloidal suspension of nanocapsules, the wall of which is constituted by the substance A and the core by the substance B, (4) if desired, the removal of all or part of the solvent or the mixture of solvents and of the non-solvent or the mixture of non-solvents so as to produce a colloidal suspension of nanocapsules of the desired concentration or to produce a powder of nanocapsules following the addition of stabilizing substances.
申请公布号 JPS63232840(A) 申请公布日期 1988.09.28
申请号 JP19870336703 申请日期 1987.12.28
申请人 CENTRE NAT RECH SCIENT 发明人 AATON FUESHI;JIYANNFUIRITSUPU DOBUISAAJIYU;FURANSHISU PIYUIZUIO
分类号 A61K9/50;A61K9/10;A61K9/51;B01J13/00;B01J13/12 主分类号 A61K9/50
代理机构 代理人
主权项
地址