发明名称 Novel derivatives.
摘要 <p>1. A compound of formula II: &lt;CHEM&gt; in which X is an acyl group of formula -R - @ - wherein R is an aliphatic or aromatic residue, A is a bridging group comprising at least one heteroatom selected from oxygen sulphur and nitrogen, in which the nitrogen is optionally substituted by C1-6 alkyl, B is a hydrophilic linking group, and W represents a group capable of reacting directly with the amino acid side chain of a protein or protein attachment group, Z is a counter anion and R1 to R4 are each independently hydrogen or an electron withdrawing moiety.</p>
申请公布号 EP0283563(A2) 申请公布日期 1988.09.28
申请号 EP19870115581 申请日期 1984.12.13
申请人 BEECHAM GROUP PLC 发明人 SMITH, RICHARD ANTHONY G. BEECHAM PHARMACEUTICALS
分类号 A61K38/16;A61K38/46;A61K39/395;A61P7/02;C07D213/71;C12N9/64;C12N9/70;C12N11/06;(IPC1-7):C07D213/71 主分类号 A61K38/16
代理机构 代理人
主权项
地址