| 摘要 |
<p>Compounds of formula (I) : <CHEM> in which X is H, F, Cl, Br, I, C1-4alkyl, CN, NO2, SO2NH2, COOH, CHO, C1-4alkoxy, CH2OH, CF3, SO2CH3, SO2CF3 or CO2CaH2a+1 wherein a is 1-5; n is 0-5; R is hydrogen or C1-4alkyl, and R<1> is OH or NHC1-4alkylNH2; and pharmaceutically acceptable salts or hydrates thereof, processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them and their use in therapy as dopamine- beta -hydroxylase inhibitors.</p> |
