Pyroglutamic acid esters, their synthesis and use in topical products

摘要

Esters of pyroglutamic acid having the structure: <IMAGE> (1) where R' and R'' are the same or different and are each represented by H or the grouping CH3[(CH2)w(CHCH3)x(CHOH)y(CH=CH)z]- where n is an integer of from 1 to 3 w is zero, or an integer of from 1 to 21 x is zero, or an integer of from 1 to 4 y is zero, or an integer of from 1 to 2 z is zero, or an integer of from 1 to 4 provided that the total number of carbon atoms in each of said grouping will not exceed 22; and provided also that when the subgrouping (CH=CH) is present, then the total number of carbon atoms in said grouping will be from 16 to 22. Synthesis, and uses of the said esters in topical compositions are also provided.