| 摘要 |
A method for prepg. the title compd. (I) comprises (1) reductively alkylating O-nitrodiphenylamine with 3-(1-phthalimido)-1chloropropane to obtain N-[3-(1-phthalimido)propyl -Oaminodiphenylamine (III), (2) reacting (III) with benzoyl chloride (iv) to N-[3-(phthalimido) propyl -O-benzamidodiphenylamine (V), (3) dehydration-ring closing of (v) to 5-(3-phthalimido-propyl)11-phenyl-5H-dibenzo[b,e [1,4 diazepin (vi), (4) reacting (vi) with hydrazine to 5-(3-aminopropyl)-11- phenyl-5H-dibenzo[b,e [1,4 diazepin (vii) (R1, and R2=H) and (5) opt. reacting (vii) with triethyl oroformate and sodium borohydride to (viii) (R1=H, R2=Me). X=halogen.
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