发明名称 USE OF ALDOSE REDUCTASE INHIBITORS TO ENHANCE INSULIN SENSITIVITY IN DIABETES MELLITUS
摘要 A method of enhancing insulin sensitivity in mammals (e.g. humans) is described. The method is based on the use of aldose reductase inhibitors to restore and preserve intracellular reduced glutathione levels, thereby enhancing the formation of insulin receptor-mixed disulfide bonds.
申请公布号 WO8806887(A1) 申请公布日期 1988.09.22
申请号 WO1988US00814 申请日期 1988.03.18
申请人 ALCON LABORATORIES, INC. 发明人 YORK, BILLIE, M., JR.
分类号 A61K31/195;A61K31/40;A61K31/415;A61K31/42;A61K31/44;A61K31/50;A61P3/08;(IPC1-7):A61K31/50 主分类号 A61K31/195
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