| 摘要 |
<p>Compound having β-adrenergic blocking properties having formula (I), wherein X is -O-, -CH2- or -----; Y is =O or a derivatized keto group, each of which is hydrolyzable or enzymatically convertible to a ketonic group; R is alkyl having from 1 to 12 carbon atoms or aralkyl having from 7 to 20 carbon atoms, and Ar is the 3 residue of a 1-alkylamino-2-propanol having a cyclic substituent at the 3-position thereof, said substituted propanol having β-adrenergic blocking properties; or an acid-addition salt thereof with a pharmaceutically acceptable acid. The invention also relates to pharmaceutical compositions containing the above compounds and methods of treatment.</p> |
