发明名称 |
1,3-dioxan-5-yl-hexenoic acids |
摘要 |
The invention provides a novel group of 4(Z)-6-([2,4,5-cis]-2-alkyl-4-o-hydroxyphenyl-1,3-dioxan-5-yl)hexenoic acids of formula I wherein R is branched alkyl of 3-5 carbon atoms and one of X and Y is hydrogen or fluoro and the other is hydrogen, and their pharmaceutically acceptable salts; together with their pharmaceutical compositions for use in treating a variety of disease conditions. Also provided are methods for the manufacture of the novel compounds. A representative compound is that in which R is t-butyl ans X and Y are both hydrogen.
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申请公布号 |
US4772625(A) |
申请公布日期 |
1988.09.20 |
申请号 |
US19860861330 |
申请日期 |
1986.05.09 |
申请人 |
IMPERIAL CHEMICAL INDUSTRIES PLC |
发明人 |
BREWSTER, ANDREW G.;SMITHERS, MICHAEL J. |
分类号 |
A61K31/335;A61K31/357;A61P7/02;A61P9/08;C07D319/06;(IPC1-7):A61K31/335 |
主分类号 |
A61K31/335 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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