发明名称 3,5-diamino-1,2,4-oxidiazoles as gastric secretion inhibitors
摘要 Novel diamino oxadiazoles, wherein one of the amine functions is connected to a basicly-substituted heterocyclic group through a linear or cyclic connecting group, which are useful for the suppression of gastric acid secretions in mammals. Compositions employing these compounds and processes for the preparation of such compounds from known N-cyano-S-methylisothiourea precursors by treatment with hydroxylamine and for alkylation of amine groups are also disclosed.
申请公布号 US4772622(A) 申请公布日期 1988.09.20
申请号 US19860874757 申请日期 1986.06.16
申请人 MERCK & CO., INC. 发明人 BRITCHER, SUSAN F.;LUMMA, JR., WILLIAM C.
分类号 C07D271/06;C07D271/07;(IPC1-7):A61K31/41;A61K31/535;C07D413/02 主分类号 C07D271/06
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