发明名称 Naphthalene anti-psoriatic agents.
摘要 <p>Psoriasis in mammals is relieved by topically administering naphthalenes of the formula: &lt;CHEM&gt; wherein: R&lt;1&gt; is lower alkoxy or optionally substituted phenoxy; R&lt;2&gt; is hydrogen, lower alkyl, optionally substituted phenyl or optionally substituted phenyl-lower-alkyl; R&lt;3&gt; is hydrogen, lower alkyl, lower alkoxy, halo, optionally substituted phenyl, optionally substituted phenyl-lower-alkyl or optionally substituted phenyl-lower-alkoxy, and m is 1 or 2; X and Y are different and are selected from the group consisting of hydrogen, R&lt;4&gt; and -C(O)W, wherein W is alkyl of one to seven carbon atoms, optionally substituted phenyl or optionally substituted benzyl; and R&lt;4&gt; is lower alkyl or optionally substituted phenyl-lower-alkyl. ce</p>
申请公布号 EP0282056(A2) 申请公布日期 1988.09.14
申请号 EP19880103799 申请日期 1988.03.10
申请人 SYNTEX (U.S.A.) INC. 发明人 VENUTI, MICHAEL C.
分类号 C07C43/20;A61K31/085;A61K31/215;A61K31/22;A61P17/00;A61P29/00;A61P43/00;C07C41/00;C07C41/01;C07C43/23;C07C43/257;C07C46/00;C07C50/10;C07C50/14;C07C50/24;C07C67/00;C07C69/017;C07C69/035;C07C69/157;C07C69/614;C07C69/78 主分类号 C07C43/20
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