发明名称 Tetraoxo compounds and pharmaceutical compositions
摘要 Tetraoxo compounds of the Formula (I) <IMAGE> (I) wherein R1 is an alkyl, alkenyl, phenylalkyl or cycloalkylalkyl group, R2 and R3 are each independently an alkyl or phenyl group or together denote an alkylene group, W is a (CH2)n-Q group, in which n is 2 to 10 and Q is (a) a displaceable leaving group X, or (b) Z-R4, where Z is a 1-piperazinyl group, and R4 is in position 4, and is hydrogen or a phenyl, substituted phenyl, N-heteroaryl or substituted N-heteroaryl group; and salts and acid addition salts of said compound, and a method for their preparation. Selected compounds of Formula (I) have been found to have central nervous system affecting activity.
申请公布号 US4771044(A) 申请公布日期 1988.09.13
申请号 US19860898043 申请日期 1986.08.19
申请人 KALI-CHEMIE PHARMA GMBH 发明人 SCHOEN, UWE;KEHRBACH, WOLFGANG;BENSON, WERNER;FUCHS, ANDREAS;RUHLAND, MICHAEL
分类号 A61K31/435;A61K31/44;A61K31/495;A61K31/505;A61P25/18;A61P25/20;A61P25/24;A61P25/26;C07D471/08;C07D471/10;(IPC1-7):C07D471/08;A61K31/395;A61K31/445 主分类号 A61K31/435
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